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Extranodal Rosai-Dorfman Disease Presenting as an Intranasal Mass

Chase Heaton Andrew Murr

Published in Journal of Case Reports in Medicine

Objective. We report the case of a 40-year-old female with biopsy-proven cutaneous extranodal Rosai-Dorfman who presented with symptoms of nasal obstruction and sinusitis. Rosai-Dorfman disease, also known as sinus histiocystosis with massive lymphadenopathy (SHML), is a rare, idiopathic disorder characterized by a benign proliferation of histiocyt...

Triple-Negative Breast Cancer among Ghanaian Women Seen at Korle-Bu Teaching Hospital

E. M. Der Richard K. Gyasi Y. Tettey T. M. Bayor L. Newman

Published in African Journal of Pathology and Microbiology

Background. Women with African ancestry in the United States and in continental Africa have been found to have exceptionally increased frequencies of triple-negative breast cancer (TNBC), prompting speculation that this risk may have an inherited basis and may at least partially explain breast cancer outcome disparities related to racial/ethnic ide...

A Novel Method for Intraoperative Reduction of the Mobile Meniscal Bearing in the Oxford Unicompartmental Knee Replaceme...

Simon M. Thompson Daniel G. G. Wilson Nimesh Patel Neil W. Bradley

Published in Journal of Orthopaedics and Trauma

Insertion of the bearing can be challenging due to patient body habitus or limited exposure when using a minimally invasive technique. We describe a novel way of inserting the bearing not previously described in the literature. The bearing is positioned on the femoral component in full flexion. Then, with a gentle extension of the knee, the bearing...

A Rare Case of Kussmaul Disease (Sialodochitis Fibrinosa)

Amrita Ray Sarah Burgin Matthew Spector

Published in Journal of Case Reports in Medicine

Sialodochitis fibrinosa (commonly known as Kussmaul disease) is a rare salivary gland disease characterized by recurrent salivary gland swelling and pain as a result of mucofibrinous plugs. Patients typically have a history of multiple recurrent glandular swellings, dehydration, decreased salivary flow, thick secretions from Stensen's, Wharton's du...

A Curious Case of a Pain in the Neck

G. Lambe A. Almanassra A. Curran

Published in Journal of Case Reports in Medicine

The article presents a case study of a 21-year-old Polish female with a short history of an enlarging, painful, midline neck swelling and odynophagia. She underwent a transcervical excision of an epidermoid cyst, which was abutting her airway posteriorly, with nasal intubation and close observation in ICU. She has enjoyed full relief of her symptom...

The Role of Harmane and Norharmane in In Vitro Dopaminergic Function

Susan M. Lantz Elvis Cuevas Bonnie L. Robinson Merle G. Paule Syed F. Ali Syed Z. Imam

Published in Journal of Drug and Alcohol Research

Background. Nicotine is one of the most frequently used drugs of abuse. It has long been speculated that in addition to nicotine , tobacco contains other compounds that reinforce addiction. Two promising candidates are the tobacco smoke constituents, harmane and norharmane. Purpose. Our study evaluated the effects of exposure to harmane and norharm...

Drinking-Related Tetrahydroharmans Counteract the Membrane Effects of Local Anesthetic Lidocaine

Hironori Tsuchiya Maki Mizogami

Published in Journal of Drug and Alcohol Research

There is a general consensus in dentistry that successful local anesthesia is frequently difficult in habitual drinkers and alcoholic patients. Neuro-active tetrahydroharmans increase in human body fluids and tissues by consuming alcoholic beverages. To understand such reduced anesthetic efficacy by the drug interaction hypothesis, we studied the i...

Phénotypes de résistance des souches d'Escherichia coli responsables des infections urinaires communautaires dans la vil...

H. Gonsu Kamga R. Nzengang M. Toukam Zacharie Sando S. Koulla Shiro

Published in African Journal of Pathology and Microbiology

Introduction. L'objectif était de rechercher les phénotypes de résistance des souches d'Escherichia coli (E. coli) dans les infections urinaires à Yaoundé. Méthodologie. Il s'agissait d'une étude prospective réalisée de juin à décembre 2012. Les souches collectées dans quelques laboratoires ont été identifiées par la galerie API 20E ; l'antibiogram...

Resistance Is Mobile: The Accelerating Evolution of Mobile Genetic Elements Encoding Resistance

Gunther Jansen C. Athena Aktipis

Published in Journal of Evolutionary Medicine

The alarming spread of antibiotic resistance threatens to turn even the most routine treatments of bacterial infection into a Sisyphean task. This is not only a result of proliferation of antibiotic resistant microbes, but also a consequence of horizontal transmission of resistance genes by mobile genetic elements able to transfer resistance genes ...

Protection against Methamphetamine-Induced Striatal Apoptosis by Epigallocatechin Gallate (EGCG) in the Mouse Brain

qingkun liu Ariela Hazan Misty Eaton Karam F. Soliman Jesus A. Angulo

Published in Journal of Drug and Alcohol Research

Methamphetamine (METH) is a psychostimulant abused worldwide and shown to be neurotoxic to both dopamine terminals and striatal neurons. Thus it would be advantageous to discover natural compounds that protect the brain from the METH-induced neural injury. In the present study, we tested the ability of epigallocatechin gallate (EGCG), the most abun...

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